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1

Double Hits in Schizophrenia.

Vorstman, Jacob A S, Olde Loohuis, Loes M, Kahn, René S, Ophoff, Roel A

Journal:

Human Molecular Genetics

Année:

2018

Langue:

english

Fichier:

PDF, 299 KB

english, 2018

2

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

Ruderfer, Douglas M., Ripke, Stephan, McQuillin, Andrew, Boocock, James, Stahl, Eli A., Pavlides, Jennifer M. Whitehead, Mullins, Niamh, Charney, Alexander W., Ori, Anil P.S., Loohuis, Loes M. Olde, D

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 22.10 MB

english, 2018

3

T225. Burden of Rare Coding Variants in the 22q11.2 Deletion Syndrome Region is Associated With Educational Attainment and Schizophrenia Risk

Breetvelt, Elemi, Smit, Karel, Loohuis, Loes Olde, Ophoff, Roel, Kahn, René, Vorstman, Jacob

Journal:

Biological Psychiatry

Année:

2018

Langue:

english

Fichier:

PDF, 44 KB

english, 2018

4

Cancer hybrid automata: Model, beliefs and therapy

Olde Loohuis, Loes, Witzel, Andreas, Mishra, Bud

Journal:

Information and Computation

Année:

2014

Langue:

english

Fichier:

PDF, 863 KB

english, 2014

5

Improving Detection of Driver Genes: Power-Law Null Model of Copy Number Variation in Cancer

Loohuis, Loes Olde, Witzel, Andreas, Mishra, Bud

Journal:

IEEE/ACM Transactions on Computational Biology and Bioinformatics

Année:

2014

Langue:

english

Fichier:

PDF, 470 KB

english, 2014

6

LOGICS AND ALGEBRAS FOR MULTIPLE PLAYERS

LOOHUIS, LOES OLDE, VENEMA, YDE

Journal:

The Review of Symbolic Logic

Année:

2010

Langue:

english

Fichier:

PDF, 236 KB

english, 2010

7

ON KNOWLEDGE AND OBLIGATION

Başķent, Can, Loohuis, Loes Olde, Parikh, Rohit

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 303 KB

english, 2012

8

Genome-wide burden of deleterious coding variants increased in schizophrenia

Loohuis, Loes M. Olde, Vorstman, Jacob A. S., Ori, Anil P., Staats, Kim A., Wang, Tina, Richards, Alexander L., Leonenko, Ganna, Walters, James T., DeYoung, Joseph, Kahn, René S., Linszen, Don, Os, Ji

Journal:

Nature Communications

Année:

2015

Langue:

english

Fichier:

PDF, 292 KB

english, 2015

9

Towards Cancer Hybrid Automata

Olde Loohuis, Loes, Witzel, Andreas, Mishra, Bud

Journal:

Electronic Proceedings in Theoretical Computer Science

Année:

2012

Langue:

english

Fichier:

PDF, 449 KB

english, 2012

10

In Vitro Human Neuronal Differentiation Validated As Genomic Model System To Study Major Psychiatric Illnesses

Ori, Anil, Bot, Merel, Molenhuis, Remco, Loohuis, Loes Olde, Ophoff, Roel

Journal:

European Neuropsychopharmacology

Année:

2017

Langue:

english

Fichier:

PDF, 41 KB

english, 2017

11

91. Structural Brain Volumes in Youth With Psychotic and Bipolar Spectrum Symptoms

Freedman, David, Jalbrzikowski, Maria, Olde Loohuis, Loes M., Ophoff, Roel A., Gur, Raquel, Bearden, Carrie

Journal:

Schizophrenia Bulletin

Année:

2017

Langue:

english

Fichier:

PDF, 49 KB

english, 2017

12

Transcriptome analysis in whole blood reveals increased microbial diversity in schizophrenia

Olde Loohuis, Loes M., Mangul, Serghei, Ori, Anil P. S., Jospin, Guillaume, Koslicki, David, Yang, Harry Taegyun, Wu, Timothy, Boks, Marco P., Lomen-Hoerth, Catherine, Wiedau-Pazos, Martina, Cantor, R

Journal:

Translational Psychiatry

Année:

2018

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2018

13

Inferring Tree Causal Models of Cancer Progression with Probability Raising

Loohuis, Loes Olde, Caravagna, Giulio, Graudenzi, Alex, Ramazzotti, Daniele, Mauri, Giancarlo, Antoniotti, Marco, Mishra, Bud, Kaderali, Lars

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 1018 KB

english, 2014

14

A Genetic Population Isolate in The Netherlands Showing Extensive Haplotype Sharing and Long Regions of Homozygosity

Somers, Metten, Olde Loohuis, Loes, Aukes, Maartje, Pasaniuc, Bogdan, de Visser, Kees, Kahn, René, Sommer, Iris, Ophoff, Roel

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 1.35 MB

english, 2017

15

Systems Biology of Cancer: A Challenging Expedition for Clinical and Quantitative Biologists

Korsunsky, Ilya, McGovern, Kathleen, LaGatta, Tom, Olde Loohuis, Loes, Grosso-Applewhite, Terri, Griffeth, Nancy, Mishra, Bud

Journal:

Frontiers in Bioengineering and Biotechnology

Année:

2014

Langue:

english

Fichier:

PDF, 2.35 MB

english, 2014

16

A longitudinal model of human neuronal differentiation for functional investigation of schizophrenia polygenic risk

Ori, Anil P.S., Bot, Merel H.M., Molenhuis, Remco T., Olde Loohuis, Loes M., Ophoff, Roel A.

Journal:

Biological Psychiatry

Année:

2018

Langue:

english

Fichier:

PDF, 19.01 MB

english, 2018

17

Structural Brain Alterations in Youth With Psychosis and Bipolar Spectrum Symptoms

Jalbrzikowski, Maria, Freedman, David, Hegarty, Catherine E., Mennigen, Eva, Karlsgodt, Katherine H., Olde Loohuis, Loes M., Ophoff, Roel A., Gur, Raquel E., Bearden, Carrie E.

Journal:

Journal of the American Academy of Child & Adolescent Psychiatry

Année:

2019

Langue:

english

Fichier:

PDF, 1.23 MB

english, 2019

18

State-Dependent Functional Dysconnectivity in Youth With Psychosis Spectrum Symptoms

Mennigen, Eva, Jolles, Dietsje D, Hegarty, Catherine E, Gupta, Mohan, Jalbrzikowski, Maria, Olde Loohuis, Loes M, Ophoff, Roel A, Karlsgodt, Katherine H, Bearden, Carrie E

Journal:

Schizophrenia Bulletin

Année:

2019

Fichier:

PDF, 1.04 MB

2019

19

SCHIZOPHRENIA AND ADULT HEIGHT SHOW AN INVERSE POLYGENIC CORRELATION WITHIN SPECIFIC FUNCTIONAL DOMAINS OF THE GENOME

Ori, Anil, Loohuis, Loes Olde, Ophoff, Roel

Journal:

European Neuropsychopharmacology

Année:

2019

Langue:

english

Fichier:

PDF, 43 KB

english, 2019

20

SA31``PERMUTATION SHRINKAGE'' APPLIED TO GWAS RESULTS INCREASES EXPLANATORY POWER OF POLYGENIC RISK SCORES BY 35%

O'Reilly, Paul, Ruan, Yunfeng, Choi, Shing Wan, Loohuis, Loes Olde

Journal:

European Neuropsychopharmacology

Année:

2019

Langue:

english

Fichier:

PDF, 50 KB

english, 2019

21

Whole blood transcriptome analysis in bipolar disorder reveals strong lithium effect

Krebs, Catharine E., Ori, Anil P.S., Vreeker, Annabel, Wu, Timothy, Cantor, Rita M., Boks, Marco P. M., Kahn, Rene S., Olde Loohuis, Loes M., Ophoff, Roel A.

Journal:

Psychological Medicine

Année:

2019

Langue:

english

Fichier:

PDF, 567 KB

english, 2019

22

THE DISTRIBUTION OF AMINO ACID CHANGES FROM CODING VARIANTS IS ALTERED IN SCHIZOPHRENIA

Loohuis, Loes Olde, Choudhury, Mudra, Ophoff, Roel

Journal:

European Neuropsychopharmacology

Année:

2019

Langue:

english

Fichier:

PDF, 47 KB

english, 2019

23

SCHIZOPHRENIA AND ADULT HEIGHT SHOW AN INVERSE POLYGENIC CORRELATION WITHIN SPECIFIC FUNCTIONAL DOMAINS OF THE GENOME

Ori, Anil, Loohuis, Loes Olde, Ophoff, Roel

Journal:

European Neuropsychopharmacology

Année:

2019

Fichier:

PDF, 43 KB

2019

24

SA31``PERMUTATION SHRINKAGE'' APPLIED TO GWAS RESULTS INCREASES EXPLANATORY POWER OF POLYGENIC RISK SCORES BY 35%

O'Reilly, Paul, Ruan, Yunfeng, Choi, Shing Wan, Loohuis, Loes Olde

Journal:

European Neuropsychopharmacology

Année:

2019

Fichier:

PDF, 50 KB

2019

25

SA102GENETIC AND CLINICAL ANALYSES OF PSYCHOSIS SPECTRUM IN A LARGE MULTI-ETHNIC YOUTH COHORT (N>8,000) REVEAL SIGNIFICANT LINK WITH ADHD

Loohuis, Loes Olde, Mennigen, Eva, Bearden, Carrie, Ophoff, Roel

Journal:

European Neuropsychopharmacology

Année:

2019

Langue:

english

Fichier:

PDF, 51 KB

english, 2019

26

An automated machine learning-based model predicts postoperative mortality using readily-extractable preoperative electronic health record data

Hill, Brian L., Brown, Robert, Gabel, Eilon, Rakocz, Nadav, Lee, Christine, Cannesson, Maxime, Baldi, Pierre, Olde Loohuis, Loes, Johnson, Ruth, Jew, Brandon, Maoz, Uri, Mahajan, Aman, Sankararaman, S

Journal:

British Journal of Anaesthesia

Année:

2019

Langue:

english

Fichier:

PDF, 754 KB

english, 2019

27

GENETICS OF SEVERE MENTAL ILLNESS: THE “PAISA PROJECT”

Lopez-Jaramillo, Carlos, Loohuis, Loes Olde, Service, Susan, Vargas, Cristian, Castano, Mauricio, Tobon, Maria Cecilia Lopez, Agudelo, Luis Guillermo, Melo, Juanita, Gur, Ruben, Gur, Raquel, Sabatti,

Journal:

European Neuropsychopharmacology

Année:

2019

Langue:

english

Fichier:

PDF, 77 KB

english, 2019

28

PHENOTYPES IN THE WHOLE GENOME SEQUENCING FOR PSYCHIATRIC DISORDERS CONSORTIUM

Vreeker, Annabel, Mansolf, Maxwell, Reise, Steven, Loohuis, Loes Olde, Ophoff, Roel, Teshiba, Terri, Bearden, Carrie, Freimer, Nelson, Bilder, Robert

Journal:

European Neuropsychopharmacology

Année:

2019

Langue:

english

Fichier:

PDF, 80 KB

english, 2019

29

LEVERAGING ELECTRONIC HOSPITAL RECORDS FOR PSYCHIATRIC PHENOTYPING

Loohuis, Loes Olde, Gomez, Juan De la Hoz, Song, Janet, Castano, Mauricio, Navarro, Juan Carlos Castro, Gallago, Cristian, Vargas, Cristian, Palacio, Juan David, Service, Susan, Escobar, Javier, Sabat

Journal:

European Neuropsychopharmacology

Année:

2019

Langue:

english

Fichier:

PDF, 73 KB

english, 2019

30

S26NLP STRATEGIES FOR ANALYZING FREE-TEXT PSYCHIATRIC ELECTRONIC HOSPITAL RECORDS

De la Hoz, Juan, Loohuis, Loes Olde, Castano, Mauricio, Song, Janet, Service, Susan, Teshiba, Terri, Gallego, Cristian, Sabatti, Chiara, Escobar, Javier, Reus, Victor, Bui, Alex, Bearden, Carrie E., L

Journal:

European Neuropsychopharmacology

Année:

2019

Langue:

english

Fichier:

PDF, 52 KB

english, 2019

31

AGE AT ONSET CHARACTERISTICS OF BIPOLAR DISORDER IN A COHORT OF 13,700 PATIENTS

Kalman, Janos, Loohuis, Loes Olde, Andlauer, Till, Stahl, Eli, Landen, Mikael, Bigdeli, Tim, McQuillin, Andrew, Mattheisen, Manuel, Als, Thomas, Forstner, Andreas J., Ruderfer, Douglas, Alda, Martin,

Journal:

European Neuropsychopharmacology

Année:

2019

Langue:

english

Fichier:

PDF, 76 KB

english, 2019

32

30 SCHIZOPHRENIA IS CHARACTERIZED BY AGE- AND SEX-SPECIFIC EFFECTS ON EPIGENETIC AGING

Ori, Anil, Loohuis, Loes Olde, Guintivano, Jerry, Clair, David St., McQuillin, Andrew, Mill, Jonathan, Sullivan, Patrick, Kahn, Rene, Horvath, Steve, Ophoff, Roel

Journal:

European Neuropsychopharmacology

Année:

2019

Fichier:

PDF, 53 KB

2019

33

GENETICS OF SEVERE MENTAL ILLNESS IN A COLOMBIAN POPULATION ISOLATE

Freimer, Nelson, Loohuis, Loes Olde, Service, Susan, Vargas, Cristian, Gomez, Juan De la Hoz, Castano, Mauricio, Gur, Ruben, Gur, Raquel E., Neale, Benjamin, Teshiba, Terri, Sabatti, Chiara, Escobar,

Journal:

European Neuropsychopharmacology

Année:

2019

Fichier:

PDF, 71 KB

2019

34

LEVERAGING ELECTRONIC HOSPITAL RECORDS FOR PSYCHIATRIC PHENOTYPING

Loohuis, Loes Olde, Gomez, Juan De la Hoz, Song, Janet, Castano, Mauricio, Navarro, Juan Carlos Castro, Gallago, Cristian, Vargas, Cristian, Palacio, Juan David, Service, Susan, Escobar, Javier, Sabat

Journal:

European Neuropsychopharmacology

Année:

2019

Fichier:

PDF, 73 KB

2019

35

S26NLP STRATEGIES FOR ANALYZING FREE-TEXT PSYCHIATRIC ELECTRONIC HOSPITAL RECORDS

De la Hoz, Juan, Loohuis, Loes Olde, Castano, Mauricio, Song, Janet, Service, Susan, Teshiba, Terri, Gallego, Cristian, Sabatti, Chiara, Escobar, Javier, Reus, Victor, Bui, Alex, Bearden, Carrie E., L

Journal:

European Neuropsychopharmacology

Année:

2019

Fichier:

PDF, 52 KB

2019

36

Contribution of common and rare variants to bipolar disorder susceptibility in extended pedigrees from population isolates

Sul, Jae Hoon, Service, Susan K., Huang, Alden Y., Ramensky, Vasily, Hwang, Sun-Goo, Teshiba, Terri M., Park, YoungJun, Ori, Anil P. S., Zhang, Zhongyang, Mullins, Niamh, Olde Loohuis, Loes M., Fears,

Journal:

Translational Psychiatry

Année:

2020

Langue:

english

Fichier:

PDF, 831 KB

english, 2020

37

Complement genes contribute sex-biased vulnerability in diverse disorders

Kamitaki, Nolan, Sekar, Aswin, Handsaker, Robert E., de Rivera, Heather, Tooley, Katherine, Morris, David L., Taylor, Kimberly E., Whelan, Christopher W., Tombleson, Philip, Loohuis, Loes M. Olde, Boe

Journal:

Année:

2020

Fichier:

PDF, 7.17 MB

2020